New prodrugs of Adefovir and Cidofovir
نویسندگان
چکیده
منابع مشابه
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15 صفحه اولClinical Potential of the Acyclic Nucleoside Phosphonates Cidofovir, Adefovir, and Tenofovir in Treatment of DNA Virus and Retrovirus Infections
متن کامل
Clinical potential of the acyclic nucleoside phosphonates cidofovir, adefovir, and tenofovir in treatment of DNA virus and retrovirus infections.
The acyclic nucleoside phosphonates HPMPC (cidofovir), PMEA (adefovir), and PMPA (tenofovir) have proved to be effective in vitro (cell culture systems) and in vivo (animal models and clinical studies) against a wide variety of DNA virus and retrovirus infections: cidofovir against herpesvirus (herpes simplex virus types 1 and 2 varicella-zoster virus, cytomegalovirus [CMV], Epstein-Barr virus,...
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ژورنال
عنوان ژورنال: Bioorganic & Medicinal Chemistry
سال: 2011
ISSN: 0968-0896
DOI: 10.1016/j.bmc.2011.04.016